DL-Phenylalanine is an essential amino acid found in common protein foods. Like other
nutrient amino acids, phenylalanine comes in L- (from the Latin levo
for left) and D- (from dextro for right) forms. The directions refer
to minor differences in the amino acids' molecular structure, as evidenced
by light refraction.
With
the help of essential cofactors (such as pyridoxine, a form of vitamin
B6, which is used with B12 to activate many of the critical ingredients), the body transforms phenylalanine in a series of steps
into the amino acid tyrosine and then into the important neurotransmitters
dopamine and noradrenaline. A 1985 study found that DLPA improved
the mood and mood stability of subjects with attention deficit disorder, and claimed that phenylalanine can increase mental alertness (Grevet et al. 2002.)
SAFETY
CONSIDERATIONS: On occasion people report headaches or nausea
from taking DLPA. Certain people should avoid all forms of phenylalanine
supplements, such as anyone with high blood pressure and women who are
pregnant or lactating. It should not be used by anyone taking MAO inhibitor
antidepressants - combining phenylalanine and MAO inhibitors can lead
to dangerously high blood pressure. Young children, anyone with psychosis,
and those suffering from malignant melanoma or the condition known as
phenylketonuria, a genetic disorder of phenylalanine metabolism, should
also not take phenylalanine supplements.
L-Tyrosine:
Tyrosine is a nonessential amino acid synthesized in the body from phenylalanine.
It is an important nutritional ingredient and factor for biosynthesis
of the brain neurotransmitters epinephrine, norepinephrine, and dopamine.
Tyrosine is also used to produce one of the major hormones, thyroxin,
which plays an important role in controlling metabolic rate, skin health,
mental health, and growth rate.
Tyrosine
has been tested on humans for increasing their endurance to anxiety
and stress under fatigue. It was proven in research studies that tyrosine
supplementation results in increased performance over a control group
(Avraham et al. 2001).
Rhodiola Rosea is an excellent adaptogen which helps supports the adrenal glands, working
with the body to reduce stress while boosting energy, balancing the
stimulants so as to not overtax the system. One
particularly interesting aspect of rhodiola is that it appears to work
differently within the body than other adaptogens -- the best known
of which is the very popular herb Siberian ginseng. Rhodiola's unique
mechanism of action excites researchers because it means this herb may
be able to provide a therapeutic alternative to established adaptogens.
Siberian
Ginseng (Eleuthero) has been used for centuries to help boost the immune system, as well
as to enhance sexual and athletic performance. This herb was hailed
last century as an "adaptogenic" (stress-protective) marvel.
In 1991 the German Commission E (the European authority on the use of
plants in healing) made it official by declaring that it was highly
effective in boosting the immune system.
In
a study of 36 children ranging in age from 3 to 17 years old, Ginseng
was administered twice a day on an empty stomach for 4 weeks. At the
end of the study, more than 70 percent of patients had experienced improvement
on a widely used measure of attention problems symptoms (Lyon MR et al 2001).
Schizandra (Schizandra chinensis) of the family Schizandraceae, is a creeping vine
with small red berries that is native to Northern China. As a traditional
medicinal herb, Schizandra, called Wu-wei-tzu in China, has been used
as a tonic for the treatment of chronic fatigue. Studies
conducted on Schizandra's effects have noted that the herb has a stimulating
effect in low doses ([Pharmacological studies on Schizandra fruit. I. General pharmacological effects of gomisin A and schizandrin (author's transl)].Maeda S, Sudo K, Aburada M, Ikeya Y, Taguchi H, Yoshioka I, Harada M.)
CAUTION:
Schizandra should not be used during pregnancy except under medical
supervision because it promotes uterine contractions during labor. Schizandra
should be avoided by persons with peptic ulcers, epilepsy and high blood
pressure.
Guarana is a South American berry that contains very high concentrations
of caffeine (guaranine) and is used as a stimulant and appetite suppressant. For
thousands of years, natives of the Amazon used the seed extract to help
maintain stamina and physical endurance. Traditionally it was also used
to assist in the relief of various ailments such as stress and nervous
tension, weight control, headaches and hangovers.
Kola
nut,
also containing caffeine, indicates a strong stimulating effect on the human
consciousness. It is used wherever there is a need for direct stimulation
to the central nervous system. Anhydrous Caffeine is also included for the same function.
Magnesium, Vitamin B3, B6, B12, C are all
direct effectors of cognitive function. A recent laboratory study from
the Massachusetts Institute of Technology (MIT) reveals that an adequate
amount of magnesium is necessary to maintain the "plasticity"
of synapses - the connectors that move information from neuron to neuron
in the brain. In this case, plasticity refers to the ability to change.
When synapses are flexible to change, learning and memory are enhanced. Other
conditions that have been associated with a magnesium deficiency include
depression, anxiety and attention deficit disorder. Research suggest low levels of magnesium
are associated with attention problems (Ghia N, Spong CY, Starbuck VN, Scialli AR, Ghidini A - Departments of Obstetrics and Gynecology and Neurology, Georgetown University Medical Center, Oct 2000.) In fact, magnesium has been called
the 'miracle nutrient' by some for its many valuable benefits.
Vitamin B's have many functions in the body, including
assisting in the synthesis of neurotransmitters and forming myelin,
which protect nerves. Magnesium is also very important; it is involved
in more than 300 metabolic reactions. At least three studies have demonstrated
that the combination of magnesium and vitamin B6 improved behavior,
decreased anxiety and aggression, and improved mobility among children
with attention problems (Nogovitsina OR et al 2006a,b; Nogovitsina OR et al 2005; Mousain-Bosc
M et al 2004).
Citrus
Aurantium is a concentrated source of synephrine -- an effective energy booster.
Bioperine is an effector of other ingredients. It is known to have enhancing and
synergizing properties and when used in a mix of ingredients, increases
the interacting potency of each.
VIEW THE LABEL
Dosage:
Each
capsule contains 820mg, with a single dose being 1 to 2 capsules for
the average person. Given the differences in physiology and lifestyle,
we recommend 1 capsule to start, increasing up to 3 capsules as indicated
by results. Most people take 2 capsules. Do not exceed 4 capsules in
one dose, and do not take more than 6 capsules in 24 hours. Drink with
plenty of fluids, fruit juice is best, eat a banana or fruit snack 20-30 minutes after
taking. Check with your physician before using stimulants, or if you
are taking other medication. Do not mix stimulants!
Conclusion:
As
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